We have a 1,200 sq ft, 3-story townhome with neighbors on the west and south sides. My home theater faces the northeast corner. The garage is below my home theater and a bedroom (office) is above.
As it relates to the adjoining neighbors, will a downfiring sub provide less boom-boom? It seems like it would, but then I can imagine that a sub firing against a wood floor might be more thunderous than ports facing an external wall on one side and an open floorplan on the other.
Did I just confuse myself? Probably. 
Incidentally, I'm working toward a 4T Hybrid system. I sit 9' from a plasma and the towers would be just shy of 5' apart.
JP
JP